Why it's used

Risperidona Tablet is a prescription medicine that is used for the treatment and maintenance of severe mental disorder (called schizophrenia). This medicine works by restricting the activity of certain natural chemicals in the brain. Risperidona Tablet is also used for the short-term treatment of serious episodes of mood swings (bipolar mania), to treat irritability associated with the inability to communicate and interact (autistic disorder), for the short-term treatment of persistent aggression in patients with moderate to severe memory loss, and for the short-term treatment of persistent aggression with antisocial behaviour (known as conduct disorder).
Risperidona Tablet may also be used along with other medicines in the treatment of certain conditions as recommended by the doctor. It is used with Lithium for the short-term treatment of periods of depression and abnormally elevated mood (mixed episodes associated with bipolar I disorder). It is also used together with Valproate for the short-term treatment of periods of depression and abnormally elevated mood (mixed episodes associated with bipolar I disorder).
When not to use
Risperidona Tablet cannot be used to treat dementia-related psychosis.
Atypical Antipsychotics
Risperidona belongs to the Atypical Antipsychotics class of medicines. Atypical antipsychotics are a group of antipsychotic drugs used to treat psychiatric conditions. These medicines are used to treat schizophrenia, bipolar disorder, autism, and used along with other medicines in the treatment of major depressive disorder.

How to use

Read the medicine guide provided by your pharmacist, your doctor, or the medicine company. If you have any questions related to Risperidona, ask your doctor or pharmacist. Use Risperidona Tablet as per the instructions provided by your doctor.
Risperidona is used with or without food.
The typical dose of Risperidona for adults is 2 mg/day divided into one or two doses and 1-2 mg dose may be added after 24 hours up to 4-8 mg/day based on patient response. The usual dose for children is 0.5 mg once daily and 0.5-1 mg dose may be added after 24 hours up to 3 mg/day based on patient response. The maximum dose for adult patients of Risperidona is 16 mg/day oral and 50 mg injection every two weeks per day. This medicine is not known to be addictive or habit-forming.
This medicine is to be used for longer periods of time. Oral Risperidona may be given for three weeks for the treatment of severe mental disorders (schizophrenia and bipolar disorder).
Discuss with your doctor if you develop new symptoms. If you have any kidney disease, the recommended dose of Risperidona should be 0.5 mg twice daily orally for the first week, can be increased for the second week to 1 mg twice or 2 mg once daily. If the daily dose of 2 mg is well tolerated, 25 mg injection of Risperidona can be given every 2 weeks. After the first injection, oral dose of Risperidona should be continued for three weeks. If you have issues with the health of your liver, the recommended dose of Risperidona should be 0.5 mg twice daily orally for the first week, can be increased for the second week to 1 mg twice or 2 mg once daily. If the daily dose of 2 mg is well tolerated, 25 mg injection of Risperidona can be given every 2 weeks. After the first injection, oral dose of Risperidona should be continued for three weeks.
Your doctor may prescribe a lower starting dose of this medicine to understand the impact on the body. Please follow your doctor's recommendations. Taking a higher dose of this medicine may increase the risk of side-effects. Older patients may see an increase in the incidence of side-effects. As a result, a lower dose may be recommended for older patients.
When stopping this medicine, some patients may experience withdrawal symptoms like vomiting, insomnia, nausea, sweating, movement disorder due to inner restlessness feeling and an urge to move, abnormal involuntary movements (dyskinesia), and involuntary muscle contraction (dystonia). You may need to taper (gradually decrease) the dose of this medicine when stopping.
If you are giving Risperidona Tablet to a child, be sure to use a product that is for use in children. Use the child's weight or age to find the right dose from the product package or medicine label. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.
If using the orally-disintegrating form of this medicine, make sure you do not consume any food or fluid 5 minutes before or after taking this medicine. Before taking the medicine out of the package, wash your hands thoroughly. Place the medicine on the tongue. Make sure you do not chew or swallow the medicine. You do not need to drink water after consuming the medicine. In certain cases, the medicine can taste slightly bitter. Also, ensure that you do not break or split the medicine.
The injection form of the medicine may be used on the buttocks muscle, the uppermost part of the arm, or top of the shoulder. Risperidona injection is intended for muscular use only. The injection form of the medicine should not be used on the vein Risperidona should be kept in room temperature after removal from the refrigerator. After the use of injection, discard the needle by snap into the orange needle protector with any hard surface like tabletop and one hand. Discard any unused portion in the syringe after use. Do not save for later use.
Avoid consuming alcohol together with Risperidona.
Medicines may be recommended for uses other than those listed in the medicine guide. You should not use Risperidona Tablet for conditions or symptoms for which it was not prescribed. Do not give Risperidona Tablet to other people, even if they have the same conditions or symptoms that you have. The use of this medicine without the advice of a doctor may cause harm.
Follow storage instructions on the product package if available. Store Risperidona Tablet at 15°-25°C (59°-77°F) for tablets, oral solution and orally disintegrating tablets and injections at 2°-8°C (36°-46°F) in the refrigerator, store not more than 25°C (77°F) temperature if refrigeration is not available and use within 7 days, away from moisture, and away from light. Store this medicine away from children and pets.

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How to take Risperidona

The dose and frequency of using Risperidona will depend on the following factors:
  • age of the patient
  • the weight of the patient
  • patient's health
  • the health of the patient's liver
  • the health of the patient's kidneys
  • response to the medicine

Risperidona Dosage

Dosage for severe mental disorder (schizophrenia)

Adult
  • Recommended: 1-2 mg/day oral dose added after 24 hours of initial dose up to 4-8 mg/day based on patient's response or 25 mg intramuscular injection every 2 weeks
  • Initial: 2 mg/day orally in one or two divided doses
  • Maximum: 16 mg/day orally or 50 mg intramuscular injection every 2 weeks
Children
  • Recommended: 0.5-1 mg/day oral dose added after 24 hours of initial dose up to 3 mg/day based on patient's response
  • Initial: 0.5 mg once daily orally
  • Maximum: 6 mg/day orally
Older Adults
  • Recommended: 0.5 mg twice daily dose added to initial dose up to 1-2 mg twice daily based on patient's response
  • Initial: 0.5 mg tablet twice daily

Dosage for periods of abnormally elevated mood (bipolar mania)

Adult
  • Recommended: 1 mg/day oral dose added or decreased after 24 hours of initial dose up to 1-6 mg/day based on patient's response
  • Initial: 2-3 mg/day orally once daily
  • Maximum: 6 mg/day orally
Children
  • Recommended: 0.5 mg or 1 mg/day oral dose added after 24 hours of initial dose up to 2.5 mg/day based on patient's response
  • Initial: 0.5 mg once daily orally
Older Adults
  • Recommended: 0.5 mg twice daily dose added to initial dose up to 1-2 mg twice daily based on patient's response
  • Initial: 0.5 mg tablet twice daily

Dosage for periods of depression and abnormally elevated mood (bipolar I disorder)

Adult
  • Recommended: 25 mg intramuscular injection every 2 weeks
  • Maximum: 50 mg intramuscular injection every 2 weeks

Dosage for irritability associated with inability to communicate and interact (autistic disorder)

Children (weighing less than 20 kg or 44.1 lb)
  • Recommended: 0.5 mg/day orally after 4 days of initial dose and in patients unresponsive to this dose after 14 days add an increment of 0.25 mg/day
  • Initial: 0.25 mg/day orally once daily
Children (weighing equal to or more than 20 kg or 44.1 lb)
  • Recommended: 1 mg/day orally after 4 days of initial dose and in patients unresponsive to this dose after 14 days add an increment of 0.5 mg/day
  • Initial: 0.5 mg/day orally once daily

Dosage for persistent aggression in patients with moderate to severe memory loss

Adult
  • Recommended: 0.25 mg tablet twice daily may be added to the starting dose every other day. In some patients, 0.5 or 1 mg tablet twice daily may benefit.
  • Initial: 0.25 mg twice daily tablet

Dosage for persistent aggression with antisocial behaviour (conduct disorder)

Children (aged 5 to 18 years with weight equal to or more than 50 kg or 110.2 lb)
  • Recommended: 0.5 mg tablet once daily may be added to the starting dose every other day. In some patients, 1 or 1.5 mg tablet once daily may benefit.
  • Initial: 0.5 mg once daily tablet
Children (aged 5 to 18 years with weight less than 50 kg or 110.2 lb)
  • Recommended: 0.25 mg tablet once daily may be added to the starting dose every other day. In some patients, 0.25, 0.5 or 0.75 mg tablet once daily may benefit.
  • Initial: 0.25 mg once daily tablet

Minimum Age

5 years

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.

Forms

Tablet
Strength: 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg and 5 mg
Orally Disintegrating Tablets
Strength: 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg
Solution
Strength: 1 mg/ml
Powder for Suspension, Extended Release Injection
Strength: 12.5 mg, 25 mg, 37.5 mg, and 50 mg
Film-Coated Tablets
Strength: 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg, and 6 mg
Coated Tablets
Strength: 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg

Special Instructions

Elderly or weaken patients
The recommended oral dose of Risperidona is 0.5 mg twice daily and it should not be increased more than 0.5 mg twice daily. After one week, the dose may be increased above 1.5 mg twice daily. For Risperidona injection, the recommended dose is 25 mg every two weeks. Along with the first injection, give oral Risperidona and continue for three weeks.
Kidney or liver dysfunction
The recommended dose of Risperidona should be 0.5 mg twice daily orally for the first week, can be increased for the second week to 1 mg twice or 2 mg once daily. If the daily dose of 2 mg is well tolerated, 25 mg injection of Risperidona can be given every 2 weeks. After the first injection, oral dose of Risperidona should be continued for three weeks.
Patients at risk of low blood pressure
The recommended oral dose of Risperidona is 0.5 mg twice daily and it should not be increased more than 0.5 mg twice daily. After one week, the dose may be increased above 1.5 mg twice daily.
Patients having a history of poor tolerability with psychotropic medicines
12.5 mg starting dose of Risperidona should be given to such patients. The efficacy study of 12.5 mg dose has not been established in clinical trials.

Missed Dose

Take the missed dose as soon as you remember. Skip the missed dose if it's time for the next dose. Do not take a double dose to make up for the dose that you may have missed.

Overdose

What to do if you overdose on Risperidona?
In case of overdose, oxygen or artificial respiration should be given for breathing problems. Stomach emptying and use of charcoal, a substance that absorbs poisons from the stomach should be done along with stool softeners. Carefully monitor heart and vital signs and also provide supportive care for low blood pressure and failure of blood circulation. Anticholinergic drugs should be given for severe extrapyramidal symptoms. Close monitoring continued until patient recovers.
Symptoms of an overdose of Risperidona
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
  • abnormally fast heart rhythm
  • drowsiness
  • extrapyramidal symptoms such as involuntary muscle contractions, motor restlessness, rigidity, slow movement, tremor, irregular body movements
  • increased heartbeat
  • low blood potassium level
  • low blood pressure
  • low blood sodium level
  • prolonged heartbeat
  • seizures
  • sleepiness
If you think you have overdosed on Risperidona Tablet, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Precautions while using Risperidona

Before you use Risperidona, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.
Before you use Risperidona Tablet, tell your doctor of your medical history including heart problem, drug-induced low level of white blood cells (leukopenia/neutropenia), seizures, drug abuse, diabetes, progressive neurological disorder (Parkinson’s disease), dementia, epilepsy, kidney problems, liver problems, an abnormally high level of the hormone prolactin, family history of blood clots, uncontrolled movement of the mouth, tongue, and face, high temperature, muscle stiffness, sweating, a lowered level of consciousness, prolonged or painful erection, heart problem, drug-induced low level of white blood cells (leukopenia/neutropenia), seizures, drug abuse, diabetes, progressive neurological disorder (Parkinson’s disease), dementia, epilepsy, kidney problems, liver problems, an abnormally high level of the hormone prolactin, family history of blood clots, uncontrolled movement of the mouth, tongue, and face, high temperature, muscle stiffness, sweating, a lowered level of consciousness, prolonged or painful erection, heart attack, heart failure, heart rhythm abnormalities (conduction abnormalities), disease of blood vessels in the brain (cerebrovascular disease), dehydration, decreased blood volume (hypovolemia), or poor tolerability to the medicines that affects the mind. A low dose of Risperidona is used in these patients and caution is advised. Before having any surgery, discuss with your doctor and dentist about medicines you use including prescription medicines, non-prescription medicines, and herbal supplements.
The use of Risperidona Tablet may change the prolactin level. This medicine may increase the level of prolactin hormone. Due to this, a milky discharge from the breast (galactorrhea), an absence of menstruation (amenorrhea), enlarged breasts in men (gynecomastia), and difficulty in erection (impotence) can occur. Long-standing high level of prolactin in the blood (hyperprolactinemia) when associated with abnormally low levels of the sex hormones (hypogonadism) may results in decreased bone density in both male and female.
The use of this medicine may change white blood cell count. Risperidona may cause a low level of white blood cells. Patients with the history of a low white blood cell count and drug-induced low white blood cell count should have their complete blood count (CBC). Regularly monitor CBC throughout the first few months of the treatment. Discontinuation of the therapy should be considered if there is a sign of a decline in white blood cell count.
The use of Risperidona Tablet may change glucose levels. The diabetic patient should undergo fasting glucose testing at the starting of the treatment and frequently during the therapy. All patients receiving Risperidona should be observed for the symptoms of high blood glucose.
Risperidona Tablet should be used only when required in patients who are pregnant or planning to become pregnant. There are increased chances of side-effects in the babies if antipsychotics are used in the third trimester. This may include withdrawal symptoms or extrapyramidal symptoms such as muscle contractions, motor restlessness, rigidity, slowness of movement, tremor and irregular jerky movements. There are some reports of nervousness (agitation), low muscle tone (hypotonia), increased muscle tone (hypertonia), tremor, respiratory distress, sleepiness, or feeding disorder. As a result, the baby should be monitored carefully. Risperidona Tablet is not safe for use in women who are breastfeeding. If you are breastfeeding, discuss with your doctor if you should either discontinue breastfeeding, or stop using this medicine during this period. This medicine may pass into breast milk. Consult with your doctor on the use of Risperidona Tablet, if you are trying to conceive.
Risperidona can make you feel sleepy. Be careful, especially while driving, while using heavy machinery, or when doing any activity that needs you to be completely alert. The consumption of alcohol with Risperidona can worsen the sleepiness. Risperidona may cause seizures in some people. Hence, you should discuss with your doctor before performing any activities where a loss of consciousness may cause harm to you or others.
Risperidona Tablet can increase your risk of getting infections/worsen existing infections. Reduce your chances of getting new infections by washing your hand regularly. Prevent cuts, bruises or injuries. Avoid people who may have infectious diseases. Avoid getting vaccinated. Risperidona may increase the risk of infections such as common cold, flu, inflammation of the lung airways, urinary tract infection, stuffy nose, pneumonia, ear infection, lower respiratory tract infection, inflammation of the pharynx or viral infection, and abscess under the skin (subcutaneous abscess).
Older patients may have a higher incidence of side-effects when using Risperidona Tablet. Elderly patients may see an increased risk of mini-stroke (transient ischaemic attack), stroke (cerebrovascular accident), urinary tract infection, swelling of the legs, lack of energy (lethargy), and cough.
Younger patients may have a higher incidence of side-effects with Risperidona Tablet. Younger patients may see an increased risk of sleepiness, fatigue, headache, increased appetite, vomiting, upper respiratory tract infection, nasal congestion, stomach pain (abdominal pain), dizziness, cough, fever, tremor, diarrhea, and involuntary urination (enuresis).

What precautions should be taken during Pregnancy and Nursing, and administering Risperidona to Children or the Older Adults?

Pregnant Women

Only When Necessary
Warning: No adequate and well-controlled studies of Risperidona have been done in pregnant women. There are increased chances of side-effects in babies if the antipsychotics are used in the third trimester. This may include withdrawal symptoms or extrapyramidal symptoms such as muscle contractions, motor restlessness, rigidity, slowness of movement, tremor, irregular jerky movements. There are some reports of nervousness (agitation), low muscle tone (hypotonia), increased muscle tone (hypertonia), tremor, respiratory distress, sleepiness, or feeding disorder. As a result, the baby should be monitored carefully.

Breastfeeding

Contraindicated or Not Recommended
Warning: This medicine may pass into breast milk.

Younger Adults Population

Possibly safe
Warning: The safety and effectiveness of Risperidona have not been confirmed for severe mental illness (schizophrenia) under the age of 13 years, for the periods of abnormally elevated mood (bipolar mania) under the age of 10 years and for communication disorder (autistic disorder) under the age of 5 years.

Older Adults Population

Possibly safe
Warning: The older adults are at an increased risk of having decreased liver, kidney and heart function. So, the dose should be adjusted according to the patient's condition because due to the decreased functioning of the kidney the risks of toxic reactions are increased.

Risperidona Side-effects

The following side-effects may commonly occur when using Risperidona Tablet. If any of these side-effects worsen or last for a long time, you should consult with your doctor:
The following side-effects may commonly occur in older patients on the use of Risperidona Tablet. Discuss with your doctor if any of these side-effects last for a long time or are severe:
The following side-effects may commonly occur in children when using Risperidona Tablet. Discuss with your doctor if any of these side-effects last for a long time or are severe:
Rarely, the use of Risperidona Tablet may cause the following side-effects:
  • a state of near-unconsciousness
  • a sudden feeling of cold (rigors)
  • abnormal coordination
  • abnormal crying
  • abnormal gait
  • absence of menstrual period (amenorrhoea)
  • accumulation of fluid
  • acne
  • an adverse drug reaction of the skin (drug eruption)
  • an eye syndrome in which iris slips towards the area of an incision during cataract surgery (intraoperative floppy iris syndrome)
  • antiemetic effect
  • back pain
  • balance disorder
  • breast discomfort
  • breast pain
  • chapped lips (cheilitis)
  • chest discomfort
  • chest pain
  • chills
  • collection of hardened feces in the rectum (faecaloma)
  • dandruff
  • dangerously excessive intake of water (polydipsia)
  • decreased libido
  • decreased response of the skin to touch and pain (hypoesthesia)
  • decreased sexual drive (sexual dysfunction)
  • decreased taste sensitivity
  • decreased weight
  • difficult urination
  • difficulty in erection (erectile dysfunction)
  • difficulty swallowing (dysphagia)
  • discharge from the breasts
  • disruption of body temperature regulation
  • disturbance in attention
  • disturbed focus
  • drug withdrawal syndrome in newborn babies
  • dry eye (xerophthalmia)
  • dry skin
  • ear pain
  • eczema
  • ejaculation disorder
  • excessive passing of gas
  • extraordinary daytime urinary frequency (pollakiuria)
  • eye movement disorder
  • eye rolling
  • eyelid margin crusting
  • fast, shallow breathing (hyperventilation)
  • feeling abnormal
  • feeling of discomfort
  • flushing
  • frequent passing of urine (micturition frequency)
  • fungal infection of the nails (onychomycosis)
  • glucose present in urine
  • hair loss
  • hives
  • inability to control bowel movements (faecal incontinence)
  • inability to pass urine
  • inability to reach orgasm (anorgasmia)
  • inappropriate antidiuretic hormone secretion
  • increase in a type of white blood cells
  • increased and decreased appetite
  • increased blood creatine phosphokinase enzyme
  • increased body temperature
  • increased heartbeat
  • increased tears
  • inflammation of the tonsils (tonsillitis)
  • infrequent menstrual periods (oligomenorrhoea)
  • involuntary laughing and crying
  • irregular or absent periods (anovulation)
  • joint stiffness
  • joint swelling
  • lack of emotion
  • lack of energy
  • lack of interest (apathy)
  • lack of muscle coordination
  • leg cramps
  • leg pain
  • low body weight (anorexia)
  • menstrual disorders
  • muscle or skeletal pain
  • muscle rigidity
  • muscle spasms
  • muscle weakness
  • nasal congestion
  • neck pain
  • nervousness
  • nightmare
  • no emotional expression
  • oversensitivity of the eyes to light
  • pain in joints (arthralgia)
  • pain in pharynx and larynx
  • painful erection (priapism)
  • palpitations
  • parkinsonian gait
  • parkinsonian rest tremor
  • photophobia
  • postural dizziness
  • procedural pain
  • prolonged and irregular heartbeat
  • psychomotor hyperactivity
  • puberty occurring at an unusually early age (precocious puberty)
  • red, itchy rash and white scales (seborrhea)
  • redness of the eye (ocular hyperaemia)
  • reduced sense of touch (hypoaesthesia)
  • ringing in the ears
  • severe itching
  • shaking of the head (head titubation)
  • skin discolouration
  • skin disorder
  • skin lesion
  • sleep walking
  • sleep-related eating disorder
  • speech disorder
  • stomach and intestinal infection
  • sugar in the urine
  • swelling of body tissues due to fluid accumulation
  • swelling of the face
  • swollen breast tissue in men
  • thickening of the skin (hyperkeratosis)
  • thirst
  • unconscious behavior (automatism)
  • unresponsive stimuli
  • urinary incontinence
  • vaginal discharge (leukorrhea)
  • vertigo
  • weight gain
The following severe side-effects may also occur when using Risperidona Tablet:
  • severe allergic reaction
    Symptoms: fever, swollen mouth, swollen face, swollen lips, swollen tongue, shortness of breath, itching, skin rash low blood pressure
    If this happens, ask your doctor immediately.
  • blood clots in the veins
    Symptoms: swelling on the affected area, pain on the affected area redness on the affected area
    If this happens, seek medical help immediately.
  • a rare life-threatening reaction to the medicines used to treat mental disorders (neuroleptic malignant syndrome) (can be possibly fatal)
    Symptoms: muscle stiffness, fever, reduced level of consciousness, sweating, altered mental status, irregular pulse, irregular blood pressure, increased or irregular heartbeat, increased creatine phosphokinase level, muscle breakdown acute kidney failure
    If this happens, stop using antipsychotic drugs immediately. The treatment should be given according to the symptoms and the patient should be monitored carefully.
  • twitching or jerking movements of the body (tardive dyskinesia)
    Symptoms: involuntary movement of the tongue, involuntary movement of the mouth involuntary movement of the face
    If this happens, contact the doctor immediately. The withdrawal of the medicine may be needed.
  • stroke (when used elderly patients with dementia related mental disorder (dementia-related psychosis)) (can be possibly fatal)
    Symptoms: mental state changes, numbness of the face, numbness of the arms, numbness of the legs slurred speech
    Do not use Risperidona in elderly patients with dementia-related psychosis.
  • painful erection (priapism)
    Symptoms: painful or prolonged erection
    If such side-effect occurs, contact your doctor immediately.
  • Symptoms: stuffy nose (rhinitis) inflammation of the pharynx (pharyngitis)
  • increased blood sugar level (diabetes mellitus) (production of excessive acids in the blood (diabetic ketoacidosis), coma or can be possibly fatal)
    Symptoms: excessive thirst, increased urination, increased appetite weakness
    If these symptoms appear, perform the test for fasting blood glucose level. The discontinuation of medicine may be needed.
  • progressive neurological disorder (Parkinson disorder)
    Symptoms: slow movement, sensation of stiffness, tightness of the muscles, sensation of freezing movement, slow shuffling walk, tremor while at rest, increased saliva, drooling, loss of expression, muscular rigidity, slowness of movement (bradykinesia), loss of muscle movement (akinesia), an inability to flex the neck forward (nuchal rigidity), parkinsonian gait blink in response to the several taps on forehead
  • decreased white blood cells
    Symptoms: low white blood cell count, fever infection
    Monitor the patients with a history of low white blood cell count during the therapy for such symptoms. Stop using Risperidona if a decrease in cell count is seen.
Your doctor has prescribed this Risperidona because they have judged that the benefits outweigh the risks posed by side-effects. Many people using this medicine do not have serious side-effects. This is not a complete list of possible side-effects for Risperidona.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Side-effects and Allergic Reactions of Risperidona by Severity and Frequency

Common Side-effects

Following are the common side-effects of this medicine:

Infrequent and Rare Side-effects

Following are the infrequent and rare side-effects of this medicine:

Severe Side-effects

Following are the severe side-effects of this medicine:

Side-effects in Older Adults

Following are the side-effects of this medicine in elderly patients:

Side-effects in Children

Following are the side-effects of this medicine in young patients:

Serious Allergic Reactions

Following are the symptoms of serious allergic reactions to this medicine:
If such symptoms occur, contact the doctor immediately.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Warnings

Brain disorders

Patients with brain disorders such as Parkinson’s disease or dementia with lewy bodies are at an increased risk when using this medicine. These patients may suffer from confusion, altered level of consciousness, postural instability with frequent falls, symptoms related to involuntary actions (extrapyramidal symptoms), and a syndrome caused by antipsychotic drugs (neuroleptic malignant syndrome). In these patients, this medicine should be used with caution.

Changes in body temperature

Patients treated with antipsychotic drugs are at an increased risk. These patients may experience an increase or decrease in body temperature. The patients who exposed to temperature extremes should use Risperidona and other antipsychotic medicines with caution.

Antiemetic effect

This medicine may cause an antiemetic effect. It may hide signs and symptoms of overdosage with several drugs or diseases such as brain and liver damage (Reye’s syndrome), intestinal obstruction, and brain tumor.

Possiblity of suicide

Patients with periods of abnormally elevated mood (bipolar mania) and severe mental disorder (schizophrenia) including adults and children are at an increased risk when using this medicine. There should be the chances of suicidal attempt in such patients. In such cases, the smallest effective dose is recommended to reduce the chances of overdose.

Prolonged erection (priapism)

A prolonged erection (priapism) may occur with the use of this medicine. The severe priapism is corrected by surgical treatment.

Postural low blood pressure

Patients with a decrease in blood pressure, while standing up from sitting or lying down using Risperidona, are at an increased risk. These patients may suffer from low blood pressure, dizziness, rapid heartbeat and fainting. In these patients, a low dose of Risperidona is recommended to reduce the risk of low blood pressure. Also, precaution is advised when using Risperidona in patients with heart diseases such as heart attack, heart failure, heart rhythm abnormalities, a disease of blood vessels in the brain (cerebrovascular disease), dehydration and decreased blood volume. The monitoring of vital signs should also be considered.

Low white blood cell count

Patients with a history of a drug-induced low level of white blood cells and existing low white blood cell count are at an increased risk when using this medicine. These patients may suffer from low white blood cell count (leukopenia, neutropenia, and deficiency of granulocytes in the blood). It is advised to monitor the patient for fever and other signs or symptoms of infection. If a severely low level of white blood cells occurs then discontinue the use of this medicine.

Problems with muscle function

Patients using Risperidona are at an increased risk. These patients may develop a problem with thinking, judgment, or movement of muscles. In these patients, precaution is advised while operating heavy machinery.

Seizures

Patients with schizophrenia and seizures are at an increased risk when using this medicine. These patients may suffer from seizures. It is advised to use this medicine with caution in the patients with a history of seizures.

Difficulty swallowing (dysphagia)

Patients with aspiration pneumonia and patients who have started antipsychotic therapy are at an increased risk. Such patients may suffer from regurgitation of food, difficulty in swallowing, and a spasm type pain (esophageal dysmotility) and sucking food into the airway (aspiration). Patients at risk for lung infection due to the inhaled food, saliva, or stomach acid into the lungs (aspiration pneumonia) should use Risperidona and other antipsychotic medicines with caution.

Dementia-related psychosis

The older adults with dementia-related psychosis are at an increased risk when using this medicine. These patients may suffer from stroke, mini-stroke and mortality. In such patients, Risperidona should not be used.

Syndrome caused by antipsychotic drugs (neuroleptic malignant syndrome)

Patients using antipsychotic drugs are at an increased risk. These patients may develop signs including muscle rigidity, fever, evidence of autonomic instability, altered mental status, the presence of myoglobin in the urine, increased level of enzyme creatinine phosphokinase and acute kidney failure. If this happens, stop using antipsychotic drugs immediately. The treatment should be given according to the symptoms and the patient should be monitored carefully.

Repetitive involuntary body movements (tardive dyskinesia)

Patients who have started antipsychotic therapy are at an increased risk. These patients may develop irreversible or involuntary muscle movements. If this happens, discontinuation of Risperidona is advised.

High blood glucose level (hyperglycemia)

Patients treated with atypical antipsychotics are at an increased risk. These patients may suffer from a high buildup of acids in the blood (ketoacidosis), coma, or fatality. If this happens, discontinue using this medicine. Some patients may need anti-diabetic treatment.

High prolactin level (hyperprolactinemia)

Patients using Risperidona and patients with existing high level of blood prolactin (hyperprolactinaemia) are at an increased risk. In these patients, prolactin levels may be increased in the blood. Due to this, a milky discharge from the breast (galactorrhea), an absence of menstruation (amenorrhea), enlarged breasts in men (gynecomastia), and difficulty in erection (impotence) can occur. Long-standing high level of prolactin in blood when associated with abnormally low levels of the sex hormones (hypogonadism) may results in decreased bone density in both male and female. When using this medicine, caution is advised especially in patients with existing high level of blood prolactin or patients with chances of prolactin-dependent tumors.

Interactions with Risperidona

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
Risperidona Tablet interacts with levodopa and dopamine agonists, which are used to treat a Parkinson's disease. When Risperidona is used with levodopa and dopamine agonists, Risperidona blocks the effect of these drugs. If the use of Risperidona with levodopa and dopamine agonists is necessary, the lowest effective dose of each drug should be used to treat end-stage Parkinson's disease.
There may be an interaction of Risperidona with drugs with blood pressure lowering effects, which are used to treat high blood pressure. If Risperidona is used with blood pressure lowering drugs, it may enhance the blood pressure lowering effect of that drugs.
Risperidona Tablet may interact with drugs acting on central nervous system and alcohol. The use of Risperidona with drugs acting on central nervous system and alcohol increases the risk of sleepiness or sedation. When Risperidona is used with other drugs that act on central nervous systems such as opiates, antihistamines and benzodiazepines and alcohol, caution should be used.
Your doctor's guidelines may need to be followed while taking this medicine along with clozapine, which is used to treat severe mental illness (schizophrenia). When Risperidona and clozapine are used together, the clearance of Risperidona is reduced.
Special instructions need to be followed while taking this medicine along with cimetidine and ranitidine, which are used to treat stomach ulcers. If the Risperidona is used with cimetidine and ranitidine, the amount of Risperidona in the blood increases.
Your doctor's guidelines may need to be followed while taking this medicine along with drugs that prolong the heartbeat (QT interval). When Risperidona is used with drugs that prolong the heartbeat such as antiarrhythmics, tricyclic antidepressants, tetracyclic antidepressants, antihistamines, other antipsychotics, antimalarials and with medicines causing electrolyte imbalance, bradycardia, or those which prevent the breakdown of Risperidona by liver, caution should be taken.
Special instructions need to be followed while taking this medicine along with carbamazepine and other enzyme inducers, which is used to control and prevent seizures. When Risperidona is used with carbamazepine and other enzyme inducers such as phenytoin and phenobarbital, the amount of metabolite of Risperidona decreases in the blood.
Risperidona Tablet interacts with fluoxetine and paroxetine, which are used to treat depression. If the Risperidona is used with fluoxetine or paroxetine, the amount of Risperidona is increased in the blood. When the use of Risperidona with fluoxetine and paroxetine is initiated or stopped, the dosage of #NAME should be re-evaluated.
There may be an interaction of Risperidona with inhibitors of CYP2D6, CYP3A4, P-gp and other CYP isoenzymes. When Risperidona and CYP2D6 inhibitors (for example, paroxetine, quinidine and fluoxetine) are used together, the amount of Risperidona increases in the blood and lowers the level of its metabolite. When Risperidona and CYP3A4, P-gp inhibitors (for example, itraconazole) are used together, the amount of active fraction of Risperidona increases in the blood. When the use of Risperidona with CYP2D6 inhibitors, CYP3A4, P-gp inhibitors is initiated or stopped, dosage adjustment may be required.
Risperidona Tablet may interact with valproate, which is used to treat epileptic disease. If the Risperidona is used with valproate, the amount of valproate in the blood is mildly increased.
Your doctor's guidelines may need to be followed while taking this medicine along with phenothiazines, which are used to treat mental disorders. When Risperidona is used with phenothiazines, may increase the amount of Risperidona in the blood.
Special instructions need to be followed while taking this medicine along with ketoconazole, which is used to treat fungal infection. When Risperidona is used with ketoconazole, the amount of Risperidona in the blood increases and the amount of metabolite of Risperidona decreases.
Risperidona Tablet interacts with rifampicin, which is used to treat bacterial infection. When Risperidona is used with rifampicin, the amount of active metabolite of Risperidona in the blood decreases.
There may be an interaction of Risperidona with paliperidone, which is used to treat mental or mood disorders. The use of Risperidona with paliperidone may lead to an increased amount of total active metabolite in the body. The use of Risperidona with paliperidone is not recommended.
Risperidona Tablet may interact with furosemide, which is used to treat fluid accumulation in heart, kidney or liver diseases. When Risperidona is used with furosemide, it can cause loss of water from the body which can be possibly fatal in the elderly patients with dementia. The use of Risperidona with furosemide should be avoided in the elderly patients with dementia.
This page does not contain all the possible interactions of Risperidona Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Interactions of Risperidona by Severity

Severe

The following medicines are usually not to be taken together without consulting with your doctor or pharmacist.

Serious

The following medicines may interact when taken together and can cause harmful effects in the body. Please consult with your doctor or pharmacist before taking these medicines together.

Moderate

The following medicines may interact when taken together and can increase your risk of harmful effects. Please consult with your doctor or pharmacist before taking these medicines together.

When should Risperidona be not used?

Severe allergy

This medicine is not recommended in patients with severe allergy to Risperidona and other components of the medicine. These patients are at increased risk of life-threatening allergic reaction or swelling due to fluid accumulation. These patients may have the following symptoms if they use this medicine:

Elderly patients with dementia related-mental disorder

This medicine is not recommended in elderly patients with dementia-related mental disorder. These patients are at increased risk of diseases in which blood supply to the brain is interrupted such as stroke, mini-stroke and it can cause fatalities. These patients may have the following symptoms if they use this medicine:
  • mental state changes
  • numbness of face
  • numbness of arms
  • numbness of legs
  • slurred speech

Persistent aggression in patients with moderate to severe memory loss (Alzheimer's dementia)

The use of Risperidona is not recommended for more than 6 weeks in such patients.

Traveling With Medication

  • Ensure that you carry enough doses of each of your prescription medicines to last the entire trip. The best place to store your medicines is in the carry on baggage. However, while flying, if carrying liquid medicines, make sure you do not go over the limits imposed for carry-on liquids.
  • While traveling overseas, make sure that you can carry each of your prescription medicines legally to your destination country. One way to ensure this is by checking with your destination country's embassy or website.
  • Make sure that you carry each of your medicines in their original packaging, which should typically include your name and address, and the details of the prescribing doctor.
  • If your travel involves crossing time zones, and you are required to take your medicine as per a fixed schedule, make sure that you adjust for the change in time.

Expired Medication

Taking a single dose of expired Risperidona is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.
This page provides information for Risperidona Tablet .
Mental Disorders
Schizophrenia
Bipolar Disorder
Alzheimer's Disease

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