Calpol 650 Tablet

Generic Name(s): Paracetamol

Why it's used

Calpol 650 Tablet is used to relieve mild to moderate pain from a headache, toothache, cold, flu, joint pain, or periods pain. This medicine works by reducing the activity of certain chemicals in the body to provide pain-relieving effects. Calpol 650 is also used to reduce fever. This medicine reduces fever by increasing the loss of heat from the body.

Calpol 650 Tablet may also be used along with other medicines in the treatment of certain conditions as recommended by the doctor. It is used with Caffeine and Aspirin to relieve the pain associated with a migraine headache. The pain is relieved because the effect of Calpol 650 gets increased when used together with caffeine or aspirin.

Nonsteroidal Anti-inflammatory Drugs

Calpol 650 belongs to the Nonsteroidal Anti-inflammatory Drugs class of medicines. Nonsteroidal anti-inflammatory drugs, also called as NSAIDs, help reduce fever, decrease pain, and prevent clotting of blood. NSAIDs also reduce inflammation in the body when used in higher doses.

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How to use

Read the directions on the product label, patient guide, or medicine guide provided by the medicine company or your pharmacist before starting to use Calpol 650 Tablet. If you have any questions related to this medicine, ask your doctor or pharmacist. Use this medicine as recommended by your doctor.

Pain medicines work best if they are used as soon as you feel any signs of pain. Calpol 650 Tablet may not work well if you delay using it until the symptoms have worsened.

Calpol 650 Tablet is used with or without food. Do not crush, chew or dissolve the medicine in water.

Typical Dosage

The typical dose of Calpol 650 is 1000 mg every 4-6 hours while symptoms last (not more than 4000 mg in one day). The maximum adult dose of Calpol 650 is 4000 mg in a day. This medicine is typically used for a period of 3 days for fever, and 10 days for pain. It takes 30 minutes for this medicine to start to work. This medicine is not known to be habit-forming.

This medicine should be used on an as-needed basis.

To decrease the possibility of side-effects, you might be recommended to use the extended-release form of this medicine by your doctor. The extended-release medicine helps in maintaining a steady level of the medicine in your body for a longer period of time. Do not crush or chew the medicine, unless indicated on the package or by your doctor.

If you are using the chewable tablet form of this medicine, make sure you chew the medicine before you swallow it.

If using the orally-disintegrating form of this medicine, make sure you do not consume any food or fluid 5 minutes before or after taking this medicine. Before taking the medicine out of the package, wash your hands thoroughly. Place the medicine on the tongue. Make sure you do not chew or swallow the medicine. You do not need to drink water after consuming the medicine. In certain cases, the medicine can taste slightly bitter. Also, ensure that you do not break or split the medicine.

If using the rapidly-dissolving tablet form of this medicine, chew this medicine or allow the medicine to dissolve on the tongue. Next, swallow the medicine with or without water.

If being used as an injection, this medicine should be given in the vein once every 4 to 6 hours. Carefully examine the injection for any change in color or presence of particles. To prevent the blockage of blood-supply caused by air bubbles, the end of the injection process should be observed properly. Use the injection within 6 hours after opening it. Do not refrigerate or freeze the injection.

If using the liquid form of this medicine, measure the dose using the provided measuring cup, spoon, or dropper. Before pouring the medicine into the measuring device, you should check the measurement markings carefully. Then, pour the dose amount into the device. After use, clean and store the measuring device in a safe place for your next use. You should not use a tablespoon or teaspoon as the dose measuring devices since it can result in an incorrect dose. If indicated on the product package, shake the medicine before use.

Talk to Your Doctor

Talk to your doctor if your condition does not improve. Tell your doctor if pain or fever lasts for a long time or gets worse, and your headache worsens more frequently or a headache develops again after every 2 days. If you have any kidney disease, a smaller dose may be prescribed to decrease the risk of kidney problems. If you have issues with the health of your liver, a lower dose may be prescribed to lower the risk of liver problems.

Use in Children

If you are giving Calpol 650 Tablet to a child, be sure to use a product that is meant for children. Before giving this medicine to a child, use the child's weight or age to find the right dose from the product package. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.

Avoid Alcohol

Avoid the consumption of alcohol with Calpol 650.

Storage

You should store Calpol 650 Tablet at 20-25°C (68-77°F), away from heat, away from moisture, and away from light. Store the medicine away from the reach of children and pets.

Medicines may be prescribed for uses other than those listed in the medicine guide. Do not use Calpol 650 Tablet for conditions for which it was not prescribed. Do not give Calpol 650 Tablet to other people who might have the same conditions or symptoms that you have. Self-medication may harm them.

Read more: What are the uses of Calpol 650?

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How to take Calpol 650

Your dose and how often you take Calpol 650 will depend on the following factors:

age
weight
patient's health
the health of the patient's liver
the health of the patient's kidneys
medicines recommended by the doctor
any other medicines being used
herbal supplements in use
response to the medicine

Calpol 650 Dosage

Dosage for mild to moderate pain

Adult (12 years or older)

Recommended: 500-1000 mg per 4-6 hours till symptoms last
Maximum: 4000 mg/day

Children (2-3 years, 24-35 lb/11-16 kg in weight)

Recommended: 160 mg every 4 hours till symptoms last
Maximum: 800 mg/day

Children (4-5 years, 36-47 lb/16-21 kg in weight)

Recommended: 240 mg every 4 hours till symptoms last
Maximum: 1200 mg/day

Children (6-8 years, 48-59 lb/22-27 kg in weight)

Recommended: 320 mg every 4 hours till symptoms last
Maximum: 1600 mg/day

Children (9-10 years, 60-71 lb/27-32 kg in weight)

Recommended: 400 mg every 4 hours till symptoms last
Maximum: 2000 mg/day

Children (11 years, 72-95 lb/33-43 kg in weight)

Recommended: 480 mg every 4 hours till symptoms last
Maximum: 2400 mg/day

Older Adults

Recommended: 500-1000 mg every 4-6 hours till symptoms last
Maximum: 4000 mg/day

Dosage for fever

Adult (12 years or older)

Recommended: 500-1000 mg every 4-6 hours till symptoms last
Maximum: 4000 mg/day

Children (2-3 years, 24-35 lb/11-16 kg in weight)

Recommended: 160 mg every 4 hours till symptoms last
Maximum: 800 mg/day

Children (4-5 years, 36-47 lb/16-21 kg in weight)

Recommended: 240 mg every 4 hours till symptoms last
Maximum: 1200 mg/day

Children (6-8 years, 48-59 lb/22-27 kg in weight)

Recommended: 320 mg every 4 hours till symptoms last
Maximum: 1600 mg/day

Children (9-10 years, 60-71 lb/27-32 kg in weight)

Recommended: 400 mg every 4 hours till symptoms last
Maximum: 2000 mg/day

Children (11 years, 72-95 lb/33-43 kg in weight)

Recommended: 480 mg every 4 hours till symptoms last
Maximum: 2400 mg/day

Older Adults

Recommended: 500-1000 mg every 4-6 hours till symptoms last
Maximum: 4000 mg/day

Minimum Age

Infants older than one month

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.

Forms

Tablet

Strength: 80 mg, 160 mg, 325 mg, 500 mg, 650 mg

Caplet

Strength: 80 mg, 160 mg, 325 mg, 500 mg, 650 mg

Solution

Strength: 80 mg/0.8mL, 80 mg/2.5mL, 160mg/5mL. 500 mg/15mL

Elixir

Strength: 32mg/1mL

Injectable solution

Strength: 10 mg/mL

Special Instructions

When eating by mouth

Use tablets and capsules without regard to food. Chewable tablets must be crushed or chewed before swallowing.

Extended-release tablet

Swallow the whole extended-release tablets without splitting, chewing, crushing or dissolving them.

Orally disintegrating tablet

Properly dissolve or chew the medicine before swallowing.

Suspension or solution

Shake well before use. Use the measuring cup or syringe for accurate dose measurement. Always use the measuring devices that come with product packaging.

Rectal suppository

Using your finger, insert the suppository into the rectum and stand up for about 15 minutes. Wash your hands thoroughly after you insert the suppository.

Missed Dose

Take the missed dose as soon as you remember. Do not take a second dose to make up for the dose that you may have missed.

Overdose

What to do if you overdose on Calpol 650?

If you have taken more than the recommended dose of Calpol 650, get medical advice immediately. If the overdose has happened within the last 1 hour, the toxic effect can be reduced by taking activated charcoal. Activated Charcoal is a form of carbon that has small, low-volume pores. These pores help trap chemicals as in the case of poisoning. N-acetylcysteine may be used as an antidote up to 24 hours after overdose of Calpol 650. It is best to use N-acetylcysteine within 8 hours of overdose. Oral methionine may be also be used if the patient is in a remote area without access to a medical facility.

Symptoms of an overdose of Calpol 650

If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:

abdominal pain
inflammation of the pancreas
kidney injury caused by damage to the kidney tubule cells
liver failure
loss of appetite
pale color of the skin
presence of an excessive amount of acids in the body
vomiting

If you think you have overdosed on Calpol 650 Tablet, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Precautions while using Calpol 650

Before you use Calpol 650, tell your doctor of your medical and health history including the following:

alcohol addiction
kidney disease
liver disease

Excessive alcohol consumption may increase the risk of liver damage.

Before you use Calpol 650 Tablet, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.

Alcohol

Avoid the consumption of alcohol with Calpol 650 Tablet. Drinking alcohol may cause may cause liver damage.

Use in Pregnancy

Calpol 650 Tablet should be used in pregnancy only when required. This medicine should be given only if the potential benefit justifies the potential risk to the baby. Calpol 650 Tablet belongs to the NSAID class of medicines. NSAIDs should not be taken after 29 weeks of pregnancy as these medicines may cause serious harm to the unborn baby.

Use while Breastfeeding

Calpol 650 is known to be safe for use in women who are breastfeeding. This medicine is found to be present in breast milk but not in a significant amount to cause any harm to the baby.

Impact on Fertility

Calpol 650 Tablet is known to be safe for use in women who are trying to conceive a baby.

Increased Risk

This medicine can cause stomach bleeding. The use of alcohol/tobacco with Calpol 650 may increase the risk. Talk to your doctor if you drink alcohol or smoke regularly. NSAID medicines, including Calpol 650, mask certain infections and prevent them from being detected.

Long Term Use

If Calpol 650 is used frequently or for a long period of time, you may develop a headache or it may worsen an existing headache.

What precautions should be taken during Pregnancy and Nursing, and administering Calpol 650 to Children or the Older Adults?

Pregnant Women

Only When Necessary

Warning: Use this medicine only if the potential benefit justifies the potential risk to the fetus.

Breastfeeding

No Known Risk

Warning: This medicine is found to be present in breast milk but not in a significant amount to cause any harm to the baby.

Younger Adults Population

Possibly safe

Warning: This medicine can be given to children after their vaccination.

Older Adults Population

Possibly safe

Warning: Limit to maximum of 4000 mg in a day.

Calpol 650 Side-effects

The following side-effects may commonly occur when using Calpol 650 Tablet. If any of these side-effects worsen or last for a long time, you should consult with your doctor:

bleeding
breathing problems
itching
mouth ulcers
skin rash
swelling of the face
swelling of the lips
swelling of the throat
swelling of the tongue

Rarely, the use of Calpol 650 Tablet may cause the following side-effects:

an allergic reaction
blood disorders
rash
swelling

The following severe side-effects may also occur when using Calpol 650 Tablet:

Serious skin reactions

Symptoms: skin reddening, skin blister skin rash

In case of severe skin reactions, discontinue the medicine and consult with your doctor.
Liver damage (possible death)

Your doctor has prescribed this Calpol 650 because they have judged that the benefits outweigh the risks posed by side-effects. Many people using this medicine do not have serious side-effects. This is not a complete list of possible side-effects for Calpol 650.

If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Side-effects and Allergic Reactions of Calpol 650 by Severity and Frequency

Common Side-effects

Following are the common side-effects of this medicine:

bleeding
bluish or purple-colored patches that appear on the skin (bruising)
breathing problems
itching
mouth ulcers
skin rash
swelling of face
swelling of the lips
throat swelling
tongue swelling

Infrequent and Rare Side-effects

Following are the infrequent and rare side-effects of this medicine:

allergic reaction (skin rashes or swelling)
blood disorders

Severe Side-effects

Following are the severe side-effects of this medicine:

blistering skin
difficulty breathing or swallowing
hives
hoarseness
itching
liver damage
skin peeling
skin rashes
skin redness
swelling of the face
swelling of the lips
swelling of the throat
swelling of the tongue

Serious Allergic Reactions

Following are the symptoms of serious allergic reactions to this medicine:

breathing problems
itching
skin rashes
swelling of the face
swelling of the lips
swelling of the throat
swelling of the tongue

If you have any symptoms of a serious side-effect, discontinue this medicine and consult with your doctor.

Warnings

Known Allergy to Calpol 650

Patients with a known allergy to this medicine or ingredients are at an increased risk when using this medicine. Before you use this medicine, carefully review the list of ingredients on the medicine label to make sure that you are not allergic to any of them. The list of ingredients may change with the brand name and the country of manufacture of the medicine.

Other Medicines Containing Calpol 650

Patients using other products containing Calpol 650 are at an increased risk because it may lead to higher level of this medicine in the body. These patients may have an increased risk of liver damage and stomach bleeding. This medicine should not be used in such patients.

Excessive Alcohol Consumption

Patients consuming three or more alcoholic drinks per day are at increased risk when using Calpol 650. Such patients may have an increased risk of liver damage. This medicine should be used with the consultation of the doctor in these patients.

Interactions with Calpol 650

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.

This page does not contain all the possible interactions of Calpol 650 Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Antiemetic Drugs

Calpol 650 Tablet interacts with domperidone, which is used to treat nausea and vomiting caused by other drugs. Domperidone increases the effects of Calpol 650.

Prokinetic Agents

There may be an interaction of Calpol 650 with metoclopramide, a medicine which is used to relieve symptoms caused by slow stomach emptying in diabetic patients. Metoclopramide increases the effects of Calpol 650.

Anticoagulants

Calpol 650 Tablet may interact with anticoagulants (warfarin and other coumarins), which are used to prevent blood clotting. The combined usage of these medicines will lead to an increased risk of bleeding.

Antineoplastic Agents

Your doctor's guidelines may need to be followed while taking this medicine along with imatinib, which is used to treat leukemia and other kinds of cancers. Do not use Calpol 650 together with Imatinib.

Antihyperlipidemic Agents

Special instructions need to be followed while taking this medicine along with cholestyramine, which is used to lower high cholesterol levels. Cholestyramine reduces the effects of Calpol 650.

Other Medicines Containing Calpol 650

Calpol 650 Tablet may interact with combination of ibuprofen and paracetamol preparations used for treatment of migraine, cold and cough. These medicines may increase the risk of an overdose of paracetamol in the body which can lead to liver damage. Do not take these medicines simultaneously while using Calpol 650.

Interactions of Calpol 650 by Severity

Severe

The following medicines are usually not to be taken together without consulting with your doctor or pharmacist.

Imatinib

Serious

The following medicines may interact when taken together and can cause harmful effects in the body. Please consult with your doctor or pharmacist before taking these medicines together.

anticoagulants (warfarin and other coumarins)
other medicines containing Paracetamol

Moderate

The following medicines may interact when taken together and can increase your risk of harmful effects. Please consult with your doctor or pharmacist before taking these medicines together.

When should Calpol 650 be not used?

Allergy

This medicine should not be used by patients who are allergic to it. These patients may have the following symptoms if they use this medicine:

skin rashes
skin reddening
skin blisters

Expired Medication

Taking a single dose of expired Calpol 650 is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

If there are disposal instructions on the package, please follow the instructions.
If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.

This page provides information for Calpol 650 Tablet .

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