Use of Ritonavir
In patients using Comit-50 along with Ritonavir, it can result in decreased blood pressure, loss of consciousness, and prolonged erection. For such patients, lower dosage of Comit-50 is recommended.
Other Erectile Dysfunction Medicines
The combined use of Comit-50 with other erectile dysfunction medicines may result in further lowering of the blood pressure. Combined use of multiple erectile dysfunction medicines is not recommended.
Non-Arteritic Anterior Ischemic Optic Neuropathy
Patients with NAION (non-arteritic anterior ischemic optic neuropathy) risk factors may face a sudden loss of vision in one or both eyes. This medicine should be used with caution and if a loss of vision occurs, the medicine should be discontinued.
Loss of Hearing
Usage of this medicine may cause a sudden decrease or loss of hearing
, ringing in ears (tinnitus
), and dizziness
. If you experience any of these symptoms, you should should stop the use of the medicine.
Existing Heart Disease
Patients with any prior history of heart diseases may have a higher risk of heart attack. Such patients should use this medicine with caution.
Some patients may have a prolonged erection lasting more than 4 hours, or a painful erection lasting more than 6 hours. In this happens, you should consult with your doctor immediately.
Low Blood Pressure
In patients using low blood pressure medicines and Comit-50 together, the blood pressure can drop significantly. This can result in dizziness
, lightheadedness, and fainting
. Such patients should first establish a stable regimen for their low blood pressure medicines and then start at a lower dose for Comit-50.