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Generalized pustular psoriasis

Symptoms of Generalized pustular psoriasis

The following features are indicative of Generalized pustular psoriasis:
  • sheeted pustules
  • pinhead-sized pustules
  • sterile pustules
  • subcorneal pustules
  • inflammatory plaques
  • erythrodermic skin

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Common Causes of Generalized pustular psoriasis

The following are the most common causes of Generalized pustular psoriasis:
  • mutations in the IL-36RN
  • mutations in CARD14
  • mutations in AP1S3 genes
  • use of drugs such as lithium, methotrexate, corticosteroids, aspirin, salicylates, progesterone
  • dental infections
  • upper respiratory infections

Risk Factors for Generalized pustular psoriasis

The following factors may increase the likelihood of Generalized pustular psoriasis:
  • patients with prior or existing psoriasis conditions
  • pregnancy
  • exposure to solar irradiation
  • irritation from topical coal tar and anthralin therapy

Prevention of Generalized pustular psoriasis

Yes, it may be possible to prevent Generalized pustular psoriasis. Prevention may be possible by doing the following:
  • encourage protein and fluid intake
  • timely treatment of infection with antibiotics
  • terminate pregnancy if there is danger to maternal life

Occurrence of Generalized pustular psoriasis

Number of Cases

The following are the number of Generalized pustular psoriasis cases seen each year worldwide:
  • Rare between 10K - 50K cases

Common Age Group

Generalized pustular psoriasis can occur at any age.

Common Gender

Generalized pustular psoriasis can occur in any gender.

Lab Tests and Procedures for Diagnosis of Generalized pustular psoriasis

The following lab tests and procedures are used to detect Generalized pustular psoriasis:
  • Skin biopsy: To diagnose the generalized pustular psoriasis
  • Blood count: To diagnose the generalized pustular psoriasis infection
  • Kidney function test: To identify the complications occur during generalized pustular psoriasis
  • Liver function test: To identify the complication occur during generalized pustular psoriasis

Complications of Generalized pustular psoriasis if untreated

Yes, Generalized pustular psoriasis causes complications if it is not treated. Below is the list of complications and problems that may arise if Generalized pustular psoriasis is left untreated:
  • can be fatal
  • delirium
  • gastrointestinal upset
  • tetany
  • cardiac failure
  • renal failure

Procedures for Treatment of Generalized pustular psoriasis

The following procedures are used to treat Generalized pustular psoriasis:
  • Phototherapy: Use of light to treat generalized pustular psoriasis

Self-care for Generalized pustular psoriasis

The following self-care actions or lifestyle changes may help in the treatment or management of Generalized pustular psoriasis:
  • encourage protein and fluid intake
  • timely treatment of infection with antibiotics
  • terminate pregnancy if there is danger to maternal life

Time for Treatment of Generalized pustular psoriasis

While time-period of treatment for each patient may vary, below is the typical time-period for Generalized pustular psoriasis to resolve if treated properly under an expert supervision:
  • In 1 - 4 weeks

Is Generalized pustular psoriasis Infectious?

Yes, Generalized pustular psoriasis is known to be infectious.

Last updated date

This page was last updated on 2/04/2019.
This page provides information for Generalized pustular psoriasis.
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