The following features are indicative of Generalized pustular psoriasis:
sheeted pustules
pinhead-sized pustules
sterile pustules
subcorneal pustules
inflammatory plaques
erythrodermic skin
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Common Causes of Generalized pustular psoriasis
The following are the most common causes of Generalized pustular psoriasis:
mutations in the IL-36RN
mutations in CARD14
mutations in AP1S3 genes
use of drugs such as lithium, methotrexate, corticosteroids, aspirin, salicylates, progesterone
dental infections
upper respiratory infections
Risk Factors for Generalized pustular psoriasis
The following factors may increase the likelihood of Generalized pustular psoriasis:
patients with prior or existing psoriasis conditions
pregnancy
exposure to solar irradiation
irritation from topical coal tar and anthralin therapy
Prevention of Generalized pustular psoriasis
Yes, it may be possible to prevent Generalized pustular psoriasis. Prevention may be possible by doing the following:
encourage protein and fluid intake
timely treatment of infection with antibiotics
terminate pregnancy if there is danger to maternal life
Occurrence of Generalized pustular psoriasis
Number of Cases
The following are the number of Generalized pustular psoriasis cases seen each year worldwide:
Rare between 10K - 50K cases
Common Age Group
Generalized pustular psoriasis can occur at any age.
Common Gender
Generalized pustular psoriasis can occur in any gender.
Lab Tests and Procedures for Diagnosis of Generalized pustular psoriasis
The following lab tests and procedures are used to detect Generalized pustular psoriasis:
Skin biopsy: To diagnose the generalized pustular psoriasis
Blood count: To diagnose the generalized pustular psoriasis infection
Kidney function test: To identify the complications occur during generalized pustular psoriasis
Liver function test: To identify the complication occur during generalized pustular psoriasis
Complications of Generalized pustular psoriasis if untreated
Yes, Generalized pustular psoriasis causes complications if it is not treated. Below is the list of complications and problems that may arise if Generalized pustular psoriasis is left untreated:
can be fatal
delirium
gastrointestinal upset
tetany
cardiac failure
renal failure
Procedures for Treatment of Generalized pustular psoriasis
The following procedures are used to treat Generalized pustular psoriasis:
Phototherapy: Use of light to treat generalized pustular psoriasis
Self-care for Generalized pustular psoriasis
The following self-care actions or lifestyle changes may help in the treatment or management of Generalized pustular psoriasis:
encourage protein and fluid intake
timely treatment of infection with antibiotics
terminate pregnancy if there is danger to maternal life
Time for Treatment of Generalized pustular psoriasis
While time-period of treatment for each patient may vary, below is the typical time-period for Generalized pustular psoriasis to resolve if treated properly under an expert supervision:
In 1 - 4 weeks
Is Generalized pustular psoriasis Infectious?
Yes, Generalized pustular psoriasis is known to be infectious.