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Subacute sclerosing panencephalitis

A rare, slowly progressive post-infectious neurological disorder affecting the central nervous system. It is characterized by seizures, ataxia, myoclonus, personality changes, spasticity, and coma. The symptoms appear several years following measles infection at an early age.

Symptoms of Subacute sclerosing panencephalitis

The following features are indicative of Subacute sclerosing panencephalitis:
  • progressive psychoneurological deterioration
  • personality changes
  • seizures
  • myoclonus
  • ataxia
  • photosensitivity
  • ocular abnormalities
  • spasticity
It is possible that Subacute sclerosing panencephalitis shows no physical symptoms and still is present in a patient.

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Common Causes of Subacute sclerosing panencephalitis

The following are the most common causes of Subacute sclerosing panencephalitis:
  • persistent defective measles virus

Risk Factors for Subacute sclerosing panencephalitis

The following factors may increase the likelihood of Subacute sclerosing panencephalitis:
  • children
  • young adults
  • before two years of age
  • adolescent age

Prevention of Subacute sclerosing panencephalitis

Yes, it may be possible to prevent Subacute sclerosing panencephalitis. Prevention may be possible by doing the following:
  • MMR vaccination

Occurrence of Subacute sclerosing panencephalitis

Number of Cases

The following are the number of Subacute sclerosing panencephalitis cases seen each year worldwide:
  • Widely occurring between 500K - 1 Million cases

Common Age Group

Subacute sclerosing panencephalitis can occur at any age.

Common Gender

Subacute sclerosing panencephalitis can occur in any gender.

Lab Tests and Procedures for Diagnosis of Subacute sclerosing panencephalitis

The following lab tests and procedures are used to detect Subacute sclerosing panencephalitis:
  • Physical examination: To examine damage to the optic nerve and retina
  • Brain MRI (Magnetic resonance imaging): To diagnose subacute sclerosing panencephalitis
  • Serum antibody titer test: To examine for signs of past measles infection
  • EEG (Electroencephalogram): To check widespread cortical dysfunction

Complications of Subacute sclerosing panencephalitis if untreated

Yes, Subacute sclerosing panencephalitis causes complications if it is not treated. Below is the list of complications and problems that may arise if Subacute sclerosing panencephalitis is left untreated:
  • can be fatal

Patient Support for Treatment of Subacute sclerosing panencephalitis

The following actions may help Subacute sclerosing panencephalitis patients:
  • Join online support group: Helps by giving more information about disease

Time for Treatment of Subacute sclerosing panencephalitis

While time-period of treatment for each patient may vary, below is the typical time-period for Subacute sclerosing panencephalitis to resolve if treated properly under an expert supervision:
  • Disease cannot be treated but only maintained or effects reduced

Related Topics

Last updated date

This page was last updated on 2/04/2019.
This page provides information for Subacute sclerosing panencephalitis.

Related Topics

Creutzfeldt-Jakob Disease

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