Why it's used

Mecobalamin is used to treat nerve damage mainly in the hands and feet. This medicine works by binding to a specific cell site and plays an important role in the synthesis of nucleic acid and protein.
Water-Soluble Vitamins
Mecobalamin belongs to a class of medicines called Water-Soluble Vitamins. Water-soluble vitamins include vitamin C and all of the vitamin B complex that performs vital functions in a variety of body system and is crucial for maintaining optimal health.

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How to use

Follow directions on the product label, information guide, and provided by your doctor before using Mecobalamin. Eat this medicine as per your doctor's instructions.

Typical Dosage

The typical adult dose ofMecobalaminis 1.5 mg daily in three divided doses.

Storage

Store Mecobalamin away from moisture, and away from light. Keep this medicine away from children and pets.
Medicines may be given for uses other than those listed in the medicine guide. Do not use Mecobalamin for symptoms for which it was not prescribed. Do not giveMecobalaminto others who may have similar symptoms as you. Self-medication can cause harm.

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How to take Mecobalamin

Your dose and how often you take Mecobalamin will depend on the following factors:
  • age

Mecobalamin Dosage

Dosage for nerve damage of hands and feet

Adult
  • Recommended: 1.5 mg daily in three divided doses based on patient's symptoms and age

Forms

Tablet
Strength: 1 mg
Capsule
Strength: 0.5 mg
Injection
Strength: 1 mg/1 ml
Tablet, coated
Strength: 15 mg
Sugar-Coated Tablet
Strength: 0.5 mg

Precautions while using Mecobalamin

Before you use Mecobalamin, discuss with your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.
The use of this medicine may change the blood pressure level. This medicine may decrease the blood pressure level.

Use in Pregnancy

It is not known if this medicine is safe for use in women who are pregnant or planning to become pregnant. Consult with your doctor before you useMecobalaminduring pregnancy or if you plan on becoming pregnant. There is no information available for the use ofMecobalaminin pregnant women.

Use while Breastfeeding

It is not known if this medicine is safe for use in women who breastfeed. Consult with your doctor before you useMecobalaminwhile breastfeeding. There is no information available for the use ofMecobalaminin breastfeeding women. However, vitamin B12 may pass into breast milk. According to an American Academy, the use of this medicine is usually suitable for breastfeeding.

What precautions should be taken during Pregnancy and Nursing, and administeringMecobalaminto Children or the Older Adults?

Pregnant Women

Unknown
Warning: There is no information available for the use ofMecobalaminin pregnant women.

Breastfeeding

Unknown
Warning: There is no information available for the use ofMecobalaminin breastfeeding women. However, vitamin B12 may pass into breast milk. According to an American Academy, the use of this medicine is usually suitable for breastfeeding.

Mecobalamin Side-effects

Rarely, the use ofMecobalaminmay cause the following side-effects:
  • burning sensation (hot sensation)
  • headache
  • nausea
  • pain at the site of injection in the muscles
  • sweating (diaphoresis)
The following severe side-effects may also occur when using Mecobalamin:
  • Stomach or intestinal disorder
    Symptoms: eating disorder, vomiting diarrhea
  • Skin reaction
    Symptoms: rash
  • Severe allergic reaction
    Symptoms: a decrease in blood pressure shortness of breath
    The patient should be carefully observed for these symptoms. If this happens, stop using this medicine immediately and take appropriate actions.
Your doctor has prescribed Mecobalamin because they judge that the benefit is greater than the risk posed by side-effects. Many people using this medicine do not have serious side-effects. This page does not list all possible side-effects of Mecobalamin.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Side-effects and Allergic Reactions ofMecobalaminby Severity and Frequency

Infrequent and Rare Side-effects

Following are the infrequent and rare side-effects of this medicine:

Severe Side-effects

Following are the severe side-effects of this medicine:
  • anaphylactoid reaction
  • anorexia
  • decrease in blood pressure
  • diarrhea
  • dyspnea
  • rash
  • vomiting

Serious Allergic Reactions

Following are the symptoms of serious allergic reactions to this medicine:
The patient should be carefully observed for these symptoms. If this happens, stop using this medicine immediately and take appropriate actions.
If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Warnings

Long Term Use

This medicine should not be used for more than one month without any purpose unless it is effective.

Handing of Mecobalamin

If the packaging sheet of this drug is swallowed, the sharp corners of this sheet may puncture the food pipe, causing hole and results in serious complications such as inflammation of the chest cavity (mediastinitis). Caution is advised over the handling of this drug.

Exposure to Light

The color ofMecobalaminmay turn reddish with exposure to light and moisture.Mecobalaminshould be used immediately when the package is opened. This medicine should not be exposed to light or moisture.

Mercury Compounds

The patients whose profession requires the contact of mercury or mercury compounds are at an increased risk when using this medicine. These patients should not use the larger doses of this medicine for a long time.

Folic Acid Deficiency

Patients with vitamin B12 deficiency are at an increased risk when using folate. When folate is used in patients having abnormal production of red blood cells with vitamin B12 deficiency, the blood-related symptoms are improved. However, the symptoms related to the nervous system may become worse. It may lead to degeneration of the lateral and posterior columns of the spinal cord (subacute combined degeneration of the spinal cord). Folic acid may mask the deficiency of vitamin B12.

Anemia

Patients with suspected deficiency of vitamin B12 are at an increased risk when using this medicine. These patients must be diagnosed first for vitamin B12 deficiency. When starting treatment immediately, the combined treatment may be started for anemia and vitamin B12 deficiency. Once the cause of anemia is identified, then the patient turned to the appropriate therapy. Daily monitoring of the blood is advised.

Interactions with Mecobalamin

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
This page does not contain all the possible interactions of Mecobalamin. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Anti-Gout Drugs

Your doctor's guidelines may need to be followed while taking this medicine along with colchicine, which is used to treat high levels of blood uric acid (gout). Absorption of Mecobalamin into the blood from the stomach and intestine may be decreased while taken with colchicine. This interaction should be taken into account while performing blood testing.

Histamine H2-Antagonists

Mecobalamin interacts with histamine H2-antagonists, which are used to treat and prevent stomach and duodenal ulcers. Absorption of Mecobalamin into the blood from the stomach and intestine may be decreased while taken with histamine H2-antagonists. This interaction should be taken into account while performing blood testing.

Antituberculosis Drugs

There may be an interaction of Mecobalamin with aminosalicylic acid, which is used to treat tuberculosis. The use of Mecobalamin with aminosalicylic acid may decrease the absorption of Mecobalamin into the blood from the stomach and intestine. Blood testing should be performed by considering this interaction.

Antibiotics

Mecobalamin may interact with neomycin, which is used to treat bacterial infections. Absorption of Mecobalamin into the blood from the stomach and intestine may be decreased while taken with neomycin. This interaction should be taken into account while performing blood testing.

Proton Pump Inhibitors

Special instructions need to be followed while taking this medicine along with omeprazole, which is used to treat stomach acid backflow and stomach ulcers. The use of Mecobalamin with omeprazole may decrease the absorption of Mecobalamin into the blood from the stomach and intestine. Blood testing should be performed by considering this interaction.

Oral Contraceptives

Mecobalamin may interact with oral contraceptives, which are used to prevent pregnancy. The use of Mecobalamin with oral contraceptives may decrease the amount of Mecobalamin in the blood from the stomach and intestine. Blood testing should be performed by considering this interaction.

Interactions ofMecobalaminby Severity

Moderate

The following medicines may interact when taken together and can increase your risk of harmful effects. Please consult with your doctor or pharmacist before taking these medicines together.

When shouldMecobalaminbe not used?

Allergy

This medicine should not be used in patients with allergy toMecobalaminor other ingredients of the drug. Patients may experience allergic reactions while using Mecobalamin.

Long Term Use

This medicine should not be used for more than one month without any purpose unless it is effective.

Expired Medication

Taking a single dose of expiredMecobalaminis unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

  • If there are disposal instructions on the package, please follow the instructions.
  • If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
  • If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
  • If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.
This page provides information for Mecobalamin .
Peripheral Neuropathy
Peripheral Neuropathy
Vitamin deficiency
Pain

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