Sodium Content
Patients with a sodium-restricted
diet are at an increased risk. In these patients, the
sodium content of this medicine must be involved in their daily sodium diet allowance.
Jaundice
Newborn babies having
jaundice are at high risk. Cloxacillin may relocate bilirubin from its protein binding sites. Target suspension and neonatal oral suspension containing
sodium benzoate may cause irritation to eyes, skin and mucous membrane. Cloxacillin should be used with caution in the treatment of jaundice in newborn babies.
Kidney Problem
The dose of Target should be adjusted in patients having a kidney problem.
Stomach Problems
Patients using
antibiotics are at an increased risk. These patients may suffer from mild to life-threatening swelling of the large intestine. It is necessary to observe the swelling of the large intestine in patients who suffer from
diarrhea while using or after the use of an antibiotic. Use of Target should be stopped and the patient is examined further if a long term or significant diarrhea or stomach
cramps are observed.
Long-Term Use
Long term use of Target may lead to overgrowth of resistant organisms.
Infections
Skin rash has occurred with a viral infection (
mononucleosis) or severe blood
cancer after the use of ampicillin. If these conditions may be suspected, avoid the use of ampicillin in such patients.
Allergic Reactions
Patients having
allergy from beta-lactam are at high risk. It is reported that patients taking beta-lactam
antibiotics may suffer from severe and irregular fatal allergic reactions. A severe allergic reaction is more likely to occur when penicillin is taken through injection as compared to oral therapy. The use of Target should be stopped and start a suitable alternative treatment if an allergic reaction occurs. Treat the side effects according to the symptoms.
Penicillins and Cephalosporins Use
Patients using penicillin with cephalosporins are at high risk. Caution is advised in such patients.
Prior Allergic Reaction
Careful monitoring should be conducted regarding prior allergic reaction to beta-lactam before starting Target treatment.
Oral Drops to Babies
Babies whose mothers are allergic to penicillin are at an increased risk while using Target neonatal oral
drops. Caution should be advised in such patients.
Aminoglycoside
Patients using aminoglycoside and Target together are at an increased risk. If these medicines are mixed in the same container, the loss of activity due to an infusion solution may occur. In such cases, these medicines should not be mixed in one container.