Rufen Tablet

Generic Name(s): Ibuprofen

Why it's used

Rufen Tablet is used to relieve mild to moderate pain from a headache, menstrual periods, muscle ache, common cold, toothache, or a backache. This medicine works by reducing the activity of a chemical in the body that causes pain and swelling. Rufen is also used to reduce fever, and to relieve pain associated with the inflammation, swelling and stiffness of the joints caused by rheumatoid arthritis and osteoarthritis.

When not to use

Rufen cannot be used to treat pain before and after the time of a heart operation.

Nonsteroidal Anti-inflammatory Drugs

Rufen belongs to a class of medicines called Nonsteroidal Anti-inflammatory Drugs. Nonsteroidal anti-inflammatory drugs, also called as NSAIDs, help reduce fever, decrease pain, and prevent clotting of blood. NSAIDs also reduce inflammation in the body when used in higher doses.

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How to use

Read the medicine guide provided by your pharmacist, your doctor, or the medicine company. If you have any questions related to Rufen, ask your doctor or pharmacist. Use Rufen Tablet as per the instructions provided by your doctor.

Rufen Tablet is a pain reliever. Pain relievers work the best if used as soon as you feel any pain. They may not work as well if they are delayed until the pain has worsened.

Rufen is used with food. To prevent a stomach upset, take this medicine with food or milk.

Typical Dosage

The typical dose of Rufen for adults is 400 mg every 4 to 6 hours (not more than 3200 mg in one day). The maximum dose for adult patients of Rufen is 3200 mg per day. This medicine is generally used for a period of 3 days for fever, and 10 days for pain. Rufen is commonly used at the same time every day. It takes 1-2 hours for this medicine to start its action. This medicine is not known to be addictive or habit-forming.

This medicine should be used on an as-needed basis. Rufen may be recommended for long-term use in the treatment of symptoms of rheumatic diseases such as arthritis and osteoarthritis.

If you are using the chewable tablet form of this medicine, make sure you chew the medicine before you swallow it.

If using the liquid form of this medicine, measure the dose using the provided measuring cup, spoon, or dropper. Before pouring the medicine into the measuring device, you should check the measurement markings carefully. Then, pour the dose amount into the device. After use, clean and store the measuring device in a safe place for your next use. You should not use a tablespoon or teaspoon as the dose measuring devices since it can result in an incorrect dose. If indicated on the product package, shake the medicine before use.

Talk to Your Doctor

Discuss with your doctor if your condition persists or worsens or if you develop new symptoms.

A lower dose of this medicine may be recommended to reduce the risk of side-effects.

Use in Children

If you are giving Rufen Tablet to a child, be sure to use a product that is for use in children. Use the child's weight or age to find the right dose from the product package or medicine label. You can also read the dosage section of this page to know the correct dose for your child. Else, consult with your doctor and follow their recommendation.

Avoid Alcohol

Avoid consuming alcohol together with Rufen.

Medicines may be recommended for uses other than those listed in the medicine guide. You should not use Rufen Tablet for conditions or symptoms for which it was not prescribed. Do not give Rufen Tablet to other people, even if they have the same conditions or symptoms that you have. The use of this medicine without the advice of a doctor may cause harm.

Storage

Follow storage instructions on the product package if available. Store Rufen Tablet at room temperature away from excess heat, away from moisture, and away from light. Store this medicine away from children and pets.

Read more: What are the uses of Rufen?

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How to take Rufen

The dose and frequency of using Rufen will depend on the following factors:

age of the patient
the weight of the patient
patient's health
the health of the patient's liver
the health of the patient's kidneys
medicines recommended by the doctor
any other medicines being used
herbal supplements being used
response to the medicine

Rufen Dosage

Dosage for painful swelling and stiffness of the joints

Adult

Recommended: 1200-3200 mg daily
Initial: 800 mg three times daily (2400 mg per day)
Maximum: 3200 mg per day

Dosage for swollen and stiffened joints

Children

Recommended: 20 mg - 30 mg per kg / 9 mg - 14 mg per lb of body weight daily. Take this dose in 3-4 parts/day.
Maximum: 40 mg per kg / 18 mg per lb of body weight daily. Take this dose in 3-4 parts/day.

Dosage for painful menstrual periods

Adult

Recommended: 400 mg every 4 hours

Children (10-12 years)

Recommended: 200-800 mg every 4 to 6 hours
Maximum: 800 mg per day

Dosage for fever

Adult

Recommended: 200-400 mg every 4 to 6 hours
Maximum: 1200 mg per day

Children (over 12 years)

Recommended: 200-400 mg every 4 to 6 hours
Maximum: 1200 mg per day

Minimum Age

6 months

Dosage calculation for children

To calculate the dosage for children please use the weight based dose calculator to calculate the appropriate dosage as per the weight of your child.

Forms

Tablet

Strength: 200 mg, 300 mg, 400 mg, 600 mg, 800 mg

Suspension

Strength: 50 mg/1.25mL, 100 mg/5mL

Injection

Strength: 5 mg/1mL, 10 mg/1mL

Missed Dose

A missed dose should be taken as early as you remember it. However, if the time for the next dose is almost there, then the missed dose should be skipped, and the regular dosing schedule should be continued. Avoid taking a repeated dose to make up for a missed dose.

Overdose

What to do if you overdose on Rufen?

If you have taken more than the recommended dose of Rufen, get medical advice immediately. If the overdose has happened within the last 1 hour, the toxic effect can be reduced by taking activated charcoal. Activated Charcoal is a form of carbon that has small and low-volume pores. These pores help trap chemicals as in the case of poisoning. In the case of adults, gastric lavage is used to minimize the toxic effect. Gastric lavage is the process of cleaning out the toxic substances of the stomach.

Symptoms of an overdose of Rufen

If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:

abdominal pain
an excessive level of acid in the body
blood in the urine
blue color around the lip, nose, and mouth
coma
confusion
convulsions
drowsiness
fast eye movements
headache
high sodium level in the blood
increased heartbeat
low blood pressure
nausea
ringing in the ears (tinnitus)
shortness of breath
slow breathing
slow heart rate
vomiting

If you think you have overdosed on Rufen Tablet, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Precautions while using Rufen

Before you use Rufen, tell your doctor of your medical and health history including the following:

asthma
bleeding in the intestines
difficulty in breathing
excess fluid build-up inside the body
high blood pressure
stomach bleeding
ulcers

Before you use Rufen Tablet, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.

Before having any surgery when using Rufen, tell your doctor and dentist about all the medicinal products you use including prescription and non-prescription medicines, and any herbal supplements.

The use of this medicine may change blood pressure. If you have high blood pressure, the use of Rufen may lead to an increase in your blood pressure. Hence, you should, monitor your blood pressure regularly.

Alcohol

Avoid the consumption of alcohol with Rufen Tablet. Drinking alcohol may cause may increase the risk of stomach and intestinal bleeding.

Use in Pregnancy

Rufen Tablet should be used in pregnancy only when required. This medicine may harm an unborn baby by causing heart disease and high blood pressure. Rufen Tablet belongs to the NSAID class of medicines. NSAIDs should not be taken after 29 weeks of pregnancy as these medicines may cause serious harm to the unborn baby.

Use while Breastfeeding

Consult with your doctor on the use of Rufen during breastfeeding. This medicine is found in breast milk but is not in a significant amount to cause any harm to the baby. However, if you use Rufen for the long-term, you should consider not breastfeeding your baby.

Impact on Fertility

Rufen Tablet may impact fertility in women. If you are trying to conceive, discuss with your doctor on the use of this medicine. The use of Rufen may reduce fertility in women trying to have a baby. Do not use Rufen in women who are having problems with having a baby. In women trying to conceive or in the first or second trimester of pregnancy, a low dose of Rufen should be used for a short time.

Dizziness

Rufen Tablet can make you feel sleepy. Be careful while driving, using machinery, or doing any other activity that needs you to be alert. The consumption of alcohol with Rufen Tablet can make you feel more sleepy.

Increased Risk

This medicine can cause stomach bleeding. The use of alcohol/tobacco with Rufen may increase the risk. Talk to your doctor if you drink alcohol or smoke regularly. Rufen should not be used in chickenpox as it increases the risk of infection. It may lead to increased risk of getting viral infections and meningitis in patients who have certain existing autoimmune disorders. This medicine may increase your sensitivity to sunlight. If this happens, limit your time outdoors and prevent sunburns. Cover your skin or use a sunscreen.

Side-effects in Older Patients

Rufen Tablet may increase side-effects in older patients. Elderly patients may see an increased risk of bleeding of the stomach and intestines, and rupture in the lining of the stomach or intestines.

Long Term Use

Long-term treatment increases the risk of heart attack, stroke, ulcers, and bleeding of the stomach and intestines.

What precautions should be taken during Pregnancy and Nursing, and administering Rufen to Children or the Older Adults?

Pregnant Women

Precaution

Warning: This medicine should be avoided in the last three months of pregnancy because it may cause heart disease in the baby.

Breastfeeding

No Known Risk

Warning: This medicine is found in breast milk but is not significant to cause any harm to the baby. If you are undergoing long-term treatment using this medicine, discuss the impact on the baby with your doctor.

Younger Adults Population

Precaution

Warning: Don't give Rufen to infants under 6 months of age, unless advised by your doctor.

Older Adults Population

Precaution

Warning: Special care should be taken in older patients.

Rufen Side-effects

The following side-effects may commonly occur when using Rufen Tablet. If any of these side-effects worsen or last for a long time, you should consult with your doctor:

abdominal pain
bleeding in the stomach or intestines
constipation
dark sticky stools with blood
diarrhea
fatigue
gas
headache
nausea
pain or uncomfortable feeling in the stomach
skin rashes
vomiting
vomiting of blood

Rarely, the use of Rufen Tablet may cause the following side-effects:

abnormal liver function
abnormally low white blood cell count
anxiety
body stops producing enough new blood cells (aplastic anaemia)
deficiency of platelets in the blood
difficulty in breathing
excess production of protein in the urine
hemolytic anemia
inflammation of the lining of the stomach
inflammation of the liver (hepatitis)
insomnia
jaundice
kidney failure
mouth ulcer
partially or completely loss of hearing
poor functioning of the kidneys
red or purple discolored spots on the skin
rupture in the wall of the gastrointestinal tract
sensitivity to the sun
severe itching of the skin
skin rashes with red, itchy and raised bumps
sore in the lining of the duodenum
swelling of the lower layer of skin
viral infection of the nose and throat
vision loss

The following severe side-effects may also occur when using Rufen Tablet:

Heart disease and stroke (possibly fatal)
Skin reactions such as serious disorder of the skin and mucous membranes (Stevens-Johnson syndrome) and redness of the skin (possibly fatal)

Symptoms: skin rashes, fever itching

The medicine should be discontinued.
Issues with the liver such as jaundice, inflammation of the liver, and loss of liver function (possibly fatal)
Gastrointestinal disorders (possibly fatal)

Symptoms: inflammation, bleeding, ulceration and rupture in the lining of the stomach, small intestine or large intestine

Your doctor has prescribed this Rufen because they have judged that the benefits outweigh the risks posed by side-effects. Many people using this medicine do not have serious side-effects. This is not a complete list of possible side-effects for Rufen.

If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Side-effects and Allergic Reactions of Rufen by Severity and Frequency

Common Side-effects

Following are the common side-effects of this medicine:

abdominal pain
constipation
diarrhea
dyspepsia
fatigue
flatulence
gastrointestinal haemorrhage
haematemesis
headache
melaena
nausea
skin rashes
vomiting

Infrequent and Rare Side-effects

Following are the infrequent and rare side-effects of this medicine:

abnormal liver function
agranulocytosis
angioedema
anxiety
aplastic anaemia
asthma
bronchospasm
duodenal ulcer
dyspnoea
gastric ulcer
gastritis
gastrointestinal perforation
haemolytic anaemia
hepatitis
insomnia
jaundice
kidney failure
leukopenia
mouth ulcer
nephrotic syndrome
neutropenia
paraesthesia
partially or completely loss of hearing
photosensitivity reaction
pruritus
purpura
rhinitis
somnolence
thrombocytopenia
tubulointerstitial nephritis
urticaria
visual loss

Severe Side-effects

Following are the severe side-effects of this medicine:

allergic reactions (facial swelling, tongue swelling, larynx swelling, dyspnoea, tachycardia, hypotension)
bullous reactions (Stevens-Johnson Syndrome, erythema multiforme and toxic epidermal necrolysis)

Side-effects in Older Adults

Following are the side-effects of this medicine in elderly patients:

gastrointestinal bleeding
gastrointestinal perforation

Serious Allergic Reactions

Following are the symptoms of serious allergic reactions to this medicine:

anaphylactic reactions

Warnings

Elderly Patients

Elderly patients are at an increased risk when using this medicine. This medicine increases the risk of stomach bleeding and rupture in the lining of the stomach or intestine in elderly patients. Special care should be taken in older patients with age greater than 65 years.

High Blood Pressure

Patients with high blood pressure are at an increased risk when using this medicine. Such patients may have an increased incidence of heart diseases. Blood pressure should be monitored closely when taking this medicine.

Fluid Retention and Heart Failure

Patients who retain water/fluid in their body or have a risk of heart failure are at an increased risk when using this medicine. This medicine should be used with precaution in patients with heart failure or fluid retention.

Ulcers or Bleeding in Stomach

Patients with a history of stomach ulcer or bleeding in the stomach and intestines are at an increased risk when using this medicine. This medicine should be started with the lowest effective dose for the shortest possible duration.

Poor Functioning of the Kidneys

Patients with kidney related health issues are at an increased risk when using this medicine. This medicine may reduce production of certain hormones and reduce the blood flow in kidneys.

Advanced Stage Kidney Disease

Patients with advanced kidney disease are at an increased risk when using this medicine. This medicine should not be used in patients with an advanced kidney disease.

Interactions with Rufen

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.

This page does not contain all the possible interactions of Rufen Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Anti-Progestational Drugs

Rufen Tablet may interact with mifepristone, which is a medicine used for abortion in early stages of pregnancy. Nonsteroidal anti-inflammatory drugs such as Rufen reduce the effects of mifepristone. Do not take Rufen for at least 8-12 days after taking mifepristone.

Non Steroidal Anti-Inflammatory Drugs

There may be an interaction of Rufen with aspirin, which is used to reduce fever and relieve mild to moderate pain. Taking Rufen along with aspirin increases the risk of stomach and intestine related health issues. Do not take this medicine if you are allergic to any NSAID medicines or Aspirin.

Diuretics

Rufen Tablet interacts with furosemide and bumetanide, which increases the production of urine. The combined usage of these medicines will lead to an increased risk of kidney damage.

Corticosteroids

Special instructions need to be followed while taking this medicine along with corticosteroids which provide relief to the inflamed areas of the body. The combined usage of these medicines will lead to an increased risk of gastrointestinal bleeding.

Angiotensin-Converting Enzyme Inhibitors

Your doctor's guidelines may need to be followed while taking this medicine along with Angiotensin-converting enzyme (ACE) inhibitors, which are used for the treatment of high blood pressure and heart failure. This medicine reduces the blood pressure lowering effect of ACE inhibitors.

Antimetabolites

Rufen Tablet may interact with methotrexate, which is a medicine used to treat cancer and painful swelling/stiffness of the joints caused by rheumatoid arthritis. This medicine may increase the harmful effects of methotrexate. Patients should take necessary precautions when taking both medicines together.

Anticoagulants

There may be an interaction of Rufen with warfarin which is used to prevent blood clotting. The combined usage of these medicines will lead to an increased risk of gastrointestinal bleeding.

Sulfonylureas

Rufen Tablet interacts with sulfonylureas, which are medicines used to treat high blood sugar (type 2 diabetes). This medicine may increase the effect of sulfonylureas.

Immunosupressants

Special instructions need to be followed while taking this medicine along with tacrolimus, which is a medicine used to prevent the rejection of certain transplanted organs. The combined usage of these medicines will lead to an increased risk of kidney damage.

Cardiac Glycosides

Your doctor's guidelines may need to be followed while taking this medicine along with cardiac glycosides, which are medicines used in the treatment of heart failure and rapid heart rate. The combined usage of these medicines may worsen the cardiac failure condition and reduce functioning of the kidneys.

Interactions of Rufen by Severity

Severe

The following medicines are usually not to be taken together without consulting with your doctor or pharmacist.

Serious

The following medicines may interact when taken together and can cause harmful effects in the body. Please consult with your doctor or pharmacist before taking these medicines together.

Moderate

The following medicines may interact when taken together and can increase your risk of harmful effects. Please consult with your doctor or pharmacist before taking these medicines together.

When should Rufen be not used?

Bleeding in the Stomach/Intestine

This medicine should not be used by patients having a stomach ulcer or having a history of gastrointestinal bleeding. Patients may have an increased risk of further bleeding in the stomach or intestines.

Heart Disease

This medicine should not be used by patients who have heart disease. These patients may have the following symptoms if they use this medicine:

weakness
slurring of speech
chest pain
shortness of breath

Allergic to Other NSAIDs

This medicine should not be used by patients who are allergic to Aspirin or any other NSAIDs. Patients may experience severe, or rarely fatal allergic reaction. These patients may have the following symptoms if they use this medicine:

life-threatening allergic reaction (anaphylaxis)

Pain during Heart Surgery

This medicine should not be used by patients who have undergone coronary artery bypass graft (CABG) surgery.

Allergic to Rufen

This medicine should not be used by patients who are allergic to it. These patients may have the following symptoms if they use this medicine:

hives
severe itching of the skin
facial swelling
tongue swelling
larynx swelling
shortness of breath
low blood pressure
increased heartbeat

Expired Medication

Taking a single dose of expired Rufen is unlikely to cause a side-effect. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. An expired medicine may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use an expired drug. You are much safer by always keeping a fresh supply of unexpired medicines.

Safe Disposal of Medication

If there are disposal instructions on the package, please follow the instructions.
If there are medicine take-back programs in your country, you should contact the respective authority to arrange for the disposal of the medicine. For example, in the USA, the Drug Enforcement Administration regularly hosts National Prescription Drug Take-Back events.
If there are no take-back programs, mix the medicine with dirt and place them in a sealed plastic bag. Throw the plastic bag in your household trash. Separately, remove all personal information including the prescription label from the medicine packaging and then dispose off the container.
If specifically indicated on the medicine package that it needs to be flushed down the toilet when no longer needed, perform the required step.

This page provides information for Rufen Tablet .

Pain

Fever

Arthritis